The Netherlands Cancer Institute
State University, Browse similar opportunities
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State University, Browse similar opportunities
We are looking for a motivated PhD student to join the Division of Biochemistry in the Netherlands Cancer Institute in the group of Titia Sixma with a keen interest in the general field of integrative structural biology and quantitative biochemistry.
The project in the laboratory of Titia Sixma is in the area of chromatin biology, studying PRC1 polycomb complexes.
The Netherlands Cancer Institute is an international center of excellence with a high standard of biological research and outstanding research facilities, with an interactive atmosphere. It is located in Amsterdam, with all its cultural amenities, close to the Schiphol airport.
The lab is located in the Department of Biochemistry, and shares an interest in structural studies coupled to functional analysis with the group of Anastassis (Tassos) Perrakis and the NKI protein facility. Facilities include the ability to produce and purify proteins in bacterial, insect, and mammalian cells, and a well-equipped macromolecular biophysics laboratory that are sites in the Instruct Centre NL . Equipment for structural analysis is spearheaded by a brand-new cryo-EM (Jeol F2 200kV with a K2 detector) and high-throughput crystallisation robotics; these local facilities are coupled with regular access to Krios cryo-EM at NeCEN (https://www.necen.nl , https://instruct-eric.eu/centre/necen---lu/ ) and to the ESRF, SLS and DLS synchrotrons, and access possibilities for NMR experiments . Dedicated computing facilities include privileged access to both CPU and GPU clusters. Both groups participate in various European and National collaborative projects and are members of the Oncode Institute .
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