Novel Approaches to Combat Antibiotic Resistance Challenge and Cash Prize up to 10,000

Date limite : 02 déc. 2019

Organisation à but non lucratif: InnoCentive

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Novel Approaches to Combat Antibiotic Resistance Challenge and Cash Prize up to 10,000

Innocentive invites talented people from all over the world to participate in chemistry and life science competition titled "Novel Approaches to Combat Antibiotic Resistance in Gram-Negative Bacteria."

Competition Theme:

Antibiotic-resistant Gram-negative infections have emerged as major concerns in hospitals, nursing homes, and other healthcare settings. To blunt the profound impact on patients and mitigate the rising costs of treating these infections, novel approaches, targets, and mechanisms are urgently needed. Therefore, the Seeker desires proposals that will reveal novel mechanisms and targets to launch drug discovery programs targeting multidrug-resistant Gram-negatives. Additionally, the Seeker desires proposals addressing insights into the factors limiting small molecule uptake and retention in Gram-negatives (“permeability and efflux”).

Submission Must Include:

  1. An explanation of the proposed Solution addressing specific Solution Requirements presented in the Detailed Description of the Challenge. This should be accompanied by a well-articulated rationale supported by literature precedents.
  2. Experimental proof-of-concept data obtained as outlined in the Detailed Description of the Challenge.


To receive an award, the Solvers will have to transfer to the Seeker their exclusive intellectual property (IP) rights to the solution. However, the Seeker will be willing to consider a licensing agreement for a partial award if exclusive IP cannot be transferred by the Solver. An award of $10,000 may be offered for a purely theoretical solution.

Merck Company (the Seeker):

For more than a century, Merck, a leading global biopharmaceutical company known as MSD outside of the United States and Canada, has been inventing for life, bringing forward medicines and vaccines for many of the world’s most challenging diseases. Through their prescription medicines, vaccines, biologic therapies, they work with customers and operate in more than 140 countries to deliver innovative health solutions. They also demonstrate the commitment to increasing access to health care through far-reaching policies, programs, and partnerships. Today, Merck continues to be at the forefront of research to advance the prevention and treatment of diseases that threaten people and communities around the world.

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